THALLIUM – The Poisoner’s Poison!

It’s not often that I come across a method to kill a character in one of my MH900414033novels with delightful efficiency and flair, but thallium is one of those chemicals. It piqued my interest some time ago and I couldn’t resist sharing it with you.

Thallium is a bluish-white metal that, in pure form, is MH900400628odorless and tasteless. When combined with chorine, it turns colorless and dissolves well in water. That means it’s not easily detected in food or drink. To me, thallium seemed like a perfect substance to kill a fictional character and, as I researched the subject in greater detail, I was right.

In years past, thallium was used as a rat poison and an ant killer, but since 1975 it’s been banned in the United States and many other countries due to safety concerns. It’s highly toxic and readily absorbed through the pores of skin.

Thallium’s extreme toxicity is due in part to its chemical similarity to potassium. It uses the body’s potassium uptake pathways to be absorbed, although it bypasses the natural self-limiting mechanism that we have for potassium ingestion. Thallium also binds with sulfur, an element essential for nutrient absorption and utilization, and it disrupts necessary cellular processes. That’s primarily why it’s such a good rat poison.

One of its more distinctive side effects is hair loss. In fact, it was once used as a MH900440370depilatory agent before its toxicity was fully appreciated. Another distinctive sign of thallium poisoning is that it damages peripheral nerves, causing excruciating pain. Victims are said to experience severe stomach cramps, nausea, and sensations similar to walking slowly over hot coals—in short, it’s a dramatic way to kill off a character you no longer need.

Thallium was very popular in the past as a murder weapon. In fact, it was often referred to as “The Poisoner’s Poison” and “The Inheritance Powder”.

Investigations into suspicious deaths have discovered thallium in tea, sodas,MH900321132soups and various foods. Radioactive thallium poisoning was said to be a favorite of KGB assassins and documentation suggests that Saddam Hussein used it to poison dissidents.

Murders from thallium have fallen out of favor in more recent mystery novels, but the substance has taken center stage in thrillers and stories of international intrigue.

But be warned! There are now diagnostic tools to detect and quantify thallium MH900448470poisoning in blood and urine to aid medical and legal investigators looking into suspicious deaths. Normal body concentrations are minimal (usually less than 1mcg/L), but a poisoned victim could have a thousand to ten thousand times this normal level (1-10mg/L). But without body fluid analysis, symptoms easily could be attributed to some other illness. It’s reasonable to assume that proper diagnosis might not be made before death occurs.

Depending on the thallium dose and the duration of exposure, a patient might recover with an antidote (Prussian blue, for example) and other life support treatments. More likely, however, the victim will be beyond hope and die a painful death within days of exposure.

Fortunately, thallium is more regulated now than it was in the past. Presently, it’s used mainly in manufacturing electronic devices and semiconductor parts. However, I’m sure a creative villain can find a reliable source when the need arises.

Thoughts? Comments? I’d love to hear them!

About James J. Murray, Fiction Writer

With experience in both pharmaceutical manufacturing and clinical patient management, medications and their impact on one’s quality of life have been my expertise. My secret passion of murder and mayhem, however, is a whole other matter. I’ve always loved reading murder mysteries and thrillers, and longed to weave such tales of my own. Drawing on my clinical expertise as a pharmacist and my infatuation with the lethal effects of drugs, my tales of murder, mayhem and medicine will have you looking over your shoulder and suspicious of anything in your medicine cabinet.
This entry was posted in About James J. Murray, About Medications/Pharmacy, Bloodless Death Scene Writing, Bloodless Death Scenes, Character development, Drug Poisoning, Drugs Used For Murder, Neurological Poisons, Pharmacy/Pharmaceuticals, Radioactive Thallium Poisoning, Thallium Poisoning, Thallium Used to Murder, The Poisoner's Poison and tagged , , , , , , , , , , , , , , , , , , , . Bookmark the permalink.

8 Responses to THALLIUM – The Poisoner’s Poison!

  1. Commonly used in China today as a rat poison. And as a result, usually suspected in mysterious flu-like symptomology there.

  2. Thanks for sharing. Someone posted a similar comment on my Facebook page about this, even stating that a co-workers wife killed her husband with thallium in China. All the best!

  3. Pingback: Mind Sieve 4/29/13 | Gloria Oliver

  4. Pingback: Need the perfect poison for your book? Check out THALLIUM, courtesy of my brother Jim Murray :) | Thomas Rydder

  5. Jacob says:

    Have you ever read/watched “a Young Poisoner’s Handbook”

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