SAMARIUM – The Good and The Bad

In the past I’ve blogged about lethal radioactive chemicals (here and here) asbosch_image possible murder weapons to use in your murder mysteries and thrillers. There is another rather dramatic radioactive agent—a beneficial medication at that—which could take center stage in the development of your next lethal plot.

Samarium is a radioisotope drug used to treat the pain associated with bone cancer. The treatment is more palliative than curative—that is, it increases a patient’s comfort level by decreasing the pain associated with metastatic bone cancer but does not cure the disease. The drug is often one of several treatments used for patients with lung, prostate and breast cancers—as well as those with osteosarcoma.

The chemical, named samarium (Sm153) lexidronam, has an interesting molecular structure such that the body treats the chemical like calcium and 642x361_Natural_Home_Remedies_for_Knee_Painselectively uptakes the drug into the body’s skeletal structure like it would calcium. Once administered, the drug is distributed throughout the body before it is absorbed into bones, where it remains.

What makes this pharmaceutical such a great murder weapon is that it’s given intravenously in a clinical setting such as a hospital, and therefore it’s relatively easy to obtain for the creative villain. There are more than 10,000 hospitals worldwide that use radioisotopes in medical treatments. Therefore, it’s a good bet that a hospital clinic that treats metastatic bone cancer would have samarium-153 on hand.

The drug emits both radioactive beta particles (the therapeutic part) and gamma rays (which make it easier to locate in the body). As with other radioactive chemicals, larger than therapeutic doses can be lethal. In one of the episodes of the television drama Law and Order Criminal Intent, a person is murdered by unknowingly ingesting three vials of samarium-153.

Samarium is available as a preservative-free solution that is clear, colorless to4_2_3_7_001 RadioPharmaVial slight amber in color, and comes in 10-ml vials that must remain frozen until used. The drug expires (technically, its therapeutic half-life) within 48 hours after being removed from the freezer.

The side effects of an overdose can be dramatic. The initial symptoms include dizziness, fatigue, joint aches, fever, chills, cough and a sore throat—in other words, flu-like symptoms occur early on that can mask the detection of a victim being poisoned until it’s too late. The symptoms progress to noticeable heart rhythm abnormalities, breathing difficulties, tingling or numbness of the extremities, excessive nosebleeds and internal bleeding that can exhibit as blood in the urine.

Certainly, this prescription drug is of great benefit to the medical community, but it can also be an exceptionally useful tool for the murder mystery writer with a creative, and possibly devious, mind.

Thoughts? Comments? I’d love to hear them!

Posted in A How To Blog on Murder Plot Ideas, A How To Blog on Murder Weapons, About James J. Murray, About Medications/Pharmacy, About Murder, All About Murder, Blog Writers, Blogging, Chemical Poisons, Chemicals Used For Murder, Designer Drug Deaths, Designer Poisons Used For Murder, Designing Murder Plots, Developing Storyline Ideas, Dramatic Murder Weapons, Drug Poisoning, Drugs For Murder Plots, Drugs Used For Murder, Drugs Used to Murder, How to Choose a Murder Weapon for a Plot Idea, Ideas for Murder Scenes, Instruments of Death, Interesting Murder Weapons, James J. Murray, James J. Murray Blog, Killing Off Characters in Writing, Killing Off Characters in Your Novel, Lethal Agents and Murder, Lethal Chemical Poisons, Lethal Chemicals in Murder Mysteries, Lethal Radioactive Agents, Murder Mayhem and Medicine, Murder Weapons Discussed, Murder With Drugs, New Blog, New Methods of Murder, New Methods To Kill Characters in Your Novel, Overdose of Samarium, Pharmacy/Pharmaceuticals, Plotting Interesting Murder Scenes, Prescription For Murder Blog, Radioactive Drugs Used for Murder, Radioactive Pharmaceuticals and Murder, Radioactive Weapons of Murder, Samarium, Samarium and Murder, Tools of Murder, Unique Murder Plots, Unique Murder Weapons | Tagged , , , , , , , , , , , , , , , , , , , , | 2 Comments

Got Milk or Brucellosis?

I’ve often blogged about biological weapons—both those used in the past and those with potential for use in your new thriller plots. The world’s population has certainly been victim to biological warfare in the past.

Viper SnakeIn 184 BC, Hannibal’s warriors hurled pots of deadly viper snakes onto the decks of enemy ships. In the 1100s, bodies of plague and smallpox victims were thrown over the city walls of enemies; and in 1495, Spaniards offered the French wine spiked with leper’s blood. These are but a few examples of the many ancient biologicals used historically in warfare, not to mention the nerve gases developed and used by Germany during the First and Second World Wars.

Today, the world has a plethora of biological agents available in secret government warehouses and there are treasure-troves of lethal weapons that can be used as the focus of intriguing thriller plots.

One such biological agent that I’ve not come across until recently is brucellosis. Farm-AnimalsThis interesting biological is a zoonotic infection, meaning that it’s a disease that can be spread between animals and humans. Six out of ten of the world’s most infectious diseases in humans are spread from animals, and brucellosis is reported to be the most common zoonotic infection.

Brucellosis is a bacterial disease originating mainly from cows—but also from swine, goats and sheep. It’s been known throughout history by various common names, including Mediterranean fever, Malta fever, gastric remittent fever and undulant fever.

One of the main sources of brucellosis infection is consumption of raw milk from farm animals. A 20-year study of the global burden of human brucellosis has determined that 500,000 people worldwide are infected with this disease every year. The areas of the world most affected include Eastern Europe, Asia, Central and South America, and regions of Africa.

SombreroMost of the cases reported in the United States are due to consumption of illegally imported, unpasteurized dairy products (milk and cheese) from Mexico. Approximately 60% of human brucellosis cases in the US now occur in California and Texas.

There is growing interest in brucellosis diagnosis and treatment by the World Health Organization (WHO) because of the growing phenomena of international tourism and population migration, as well as the potential to use the Brucella bacterium as a biological weapon.

Death from a brucellosis infection is rare, but recovery from this debilitating illness can take weeks and up to several months. The initial symptoms of fever and sweats, anorexia and headaches, fatigue to general malaise, and pain in the muscles, joints and spine can progress in severity over time. Serious neurological complications and endocarditis can also occur.

The solution to the global spread of brucellosis in humans is two-fold: 1) the control and elimination of the disease in animals via culling of the infected animals and animal vaccinations; and 2) pasteurization of milk prior to consumption or use in making cheeses and other food products.

I love milk and drink lots of it. But, the next time I see a commercial for “GotGlass of Milk Milk?” I’ll remind myself to be assured that what I consume doesn’t have brucellosis riding along with it.

Thoughts? Comments? I’d love to hear them!

Posted in A How To Blog on Murder Plot Ideas, A How To Blog on Murder Weapons, About James J. Murray, About Medications/Pharmacy, About Murder, About Writing, All About Murder, Biological Poisons, Biological Warfare, Biological Warfare Treatments, Biological Weapons, Bioterrorism, Blog About Poisons in Fiction Writing, Blog Writers, Blogging, Bloodless Death Scene Writing, Bloodless Death Scenes, Brucellosis, Brucellosis - A Biological Weapon, Chemical Poisons, Chemical Weapons Discussions, Chemicals Used For Murder, Choosing How a Character Should Die in a Story, Deadly Food, Deciding How to Kill Off a Character in a Novel, Designing Murder Plots, Developing Storyline Ideas, Dramatic Murder Weapons, Food Source Poisons, Foods That Kill, Foods Used For Murder, How to Choose a Murder Weapon for a Plot Idea, How To Write A BloodLess Murder Scene, Ideas for Murder Scenes, Instruments of Death, Interesting Murder Weapons, James J. Murray Blog, Killing a Villain in a Novel, Killing Off Characters in Writing, Killing Off Characters in Your Novel, Killing With Lethal Microbes, Lethal Agents and Murder, Lethal Biologicals, Methods of Murder, Microbes Used To Murder, Murder Mayhem and Medicine, Murder Weapons Discussed, Murder With Food, Neurotoxin Poisons, New Blog, New Methods of Murder, New Methods To Kill Characters in Your Novel, Plotting Interesting Murder Scenes, Plotting Murder Scenes, Prescription For Murder Blog, Preventing Human Brucellosis, The Science of Murder, Tools of Murder, Unique Murder Plots, Unique Murder Weapons, Ways to Murder, Writing Dramatic Murder Scenes, Zoonotic Infections | Tagged , , , , , , , , , , , , , , , , , , , , , , | 4 Comments

Teaching an Old Drug New Tricks

I’ve written in previous blogs (here, here and here) about the increasing danger of drug resistant bacteria—that one day we may find that certain bacteria have evolved to be resistant to ALL known antibiotics and that the so-called “Golden Age of Antibiotics” may be coming to an end.

MH900185160Medical experts are increasingly concerned that today’s most powerful and most often used antibiotics are sometimes not effective against common infections of the urinary and respiratory tracts. They suggest that at some point people may die from these common ailments, just as it was in the early 1900s. Minor infections may become life-threatening crises, and pneumonia and TB may be much more difficult to treat.

Drugs develop resistance to antibiotics in two simple ways: 1)MH900407492 mutations happen in the bacteria genomes to allow them to withstand antibiotic attacks, and 2) bacteria become infected with small pieces of foreign DNA that carries a gene for antibiotic resistance (sort of like jumping from one bug to another).

Much of the drug resistant bacteria studies indicate that overuse of antibiotics in common products such as household cleaners and hand sanitizers can lead to mutations that make bacteria resistant to antimicrobial therapies. Other studies indicate that antibiotics used to wash produce and those used at animal farms are overused and can lead to drug resistant strains of bacteria.

The end result is that bacteria present in our environment eventually become resistant to some of our commonly-used antibiotics. The antibiotics that are used to grow our food and those added to cleaning products eventually lose their effectiveness when prescribed to treat serious infections.

In recent years, drug resistance has increased at a greater rate than the development of new antibiotics to treat these drug-Prescription-Drugsresistant microbes. In situations where commonly-used antibiotics are no longer effective, healthcare providers are turning to some older antibiotics to treat these super bugs.

One such older drug that’s getting a second look is colistin (polymyxin E).  It was first developed in Japan in 1949 and became available for clinical use in 1959, primarily for the treatment of gram-negative infections (E. coli, salmonella, pseudomonas, helicobacter, legionella, and a few others bacteria). Although colistin is an effective antimicrobial agent against these stubborn bugs, colistin fell out of favor when newer, more effective drugs with less side effects became available.

These newer, safer and more effective replacements for colistin, however, areSpinach presently used to prevent such contamination in food products and to sanitize kitchen and bathroom surfaces, as well as being used in hand sanitizers. The abundant use of these once-effective antibiotics have allowed certain bacteria to develop resistance through mutations and DNA transference.

Therefore, medical professionals are beginning to use older drugs, like colistin, to effectively treat drug resistant infections such as CRE, a super bug that is reported to kill up to 50% of infected patients.

The news regarding the successful use of colistin is not all rosy, however. The very first case of a colistin-resistant bacterial infection has reached the United States. A 49-year-old women in Pennsylvania has contracted a colistin-resistant urinary tract infection. Fortunately, her doctors were able to treat her with other antibiotics and she will survive.

The battle to keep an arsenal of effective antibiotics available is rapidly losing ground to evermore drug-resistant bacterial strains. I sometimes wonder who will win the battle!

Thoughts? Comments? I’d love to hear them!

Posted in About James J. Murray, About Medications/Pharmacy, Antibiotic Discovery Void, Antibiotic Overuse, Antibiotic Resistance, Antibiotic Resistant Bacteria, Antibiotics in Agriculture, Antibiotics of the Past in Use Today, Attack of Bacteria, Blog Writers, Blogging, Colistin Use, CRE Prevention, Drug Resistant Bacteria, Flesh Eating Bacteria, Future of Drug Manufacturing, Future of Prescription Drug Distribution, Ineffective Antibiotic Therapy, Ineffective Antibiotics, James J. Murray Blog, Lack of New Antibiotic Drugs, Medication Shortages in the US, Murder Mayhem and Medicine, New Blog, New Uses for Old Drugs, Our nation's drug supply, Over-Prescribing of Antibiotics, Overuse of Antibiotics, Pharmacy/Pharmaceuticals, Prescription For Murder Blog, Prescription Prescribing Practices, The Practice of Pharmacy | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Water Poisons

MH900432792“Water, water everywhere and not a drop to drink.” This quote from The Rhyme of the Ancient Mariner by English poet Samuel Taylor Coleridge came to mind recently while watching news feeds regarding a spectacular water contamination of toxic blooms along some of Florida’s most popular shorelines.

Life cannot exist without water and that’s why NASA’s primary test for life on other planets is evidence of water. But water is never pure. It’s the most common solvent, and the water in our lakes, rivers and seas can become extremely toxic—even deadly.

Toxic blooms that create adverse effects are called Harmful Algal Blooms (HABs). They grow naturally as a response to changes in the chemical content of water (like increases in nitrogen and phosphorus from fertilizer runoff) or changes in pH (how acid or alkaline the water is). HABs can also deplete the oxygen and block sunlight from water, thereby adversely affecting marine life.

HAB toxins also harm humans who come into contact with them.MH900438738 There are a couple of HABs that create the most havoc, but the most prevalent this year are Cyanobacteria (blue-green algae or pond scum).

There are both toxic and non-toxic strains of these algae. Spirulina is a type of blue-green algae that’s non-toxic, specifically because it’s free of microcystins (more on that in a minute). The toxic varieties (like what was reported in the news this past week) should never be ingested, even accidentally while swimming in contaminated waters.

Consumption produces abdominal cramps, nausea, diarrhea and vomiting. Prolonged skin exposure causes irritating rashes. More concentrated exposure can lead to liver damage and digestive problems. They also adversely affect the nervous system since they are neurotoxins (adversely affecting our brain and peripheral nerves).

Most varieties of Cyanobacteria (50–70%) are harmful, and that’s because they contain naturally-occurring neurotoxins in their cells. These toxins are called microcystins and are primarily responsible for the health issues associated with toxic blooms.

Microcystins are extremely stable (both to cold and heat as well as to changes in pH). For that reason, boiling water does not remove them. Ultra-filtration is the only safe way to purify water contaminated with such toxins.

Florida BeachSo water is not only the giver of life. It can also take away life when there’s toxic baggage dissolved in or floating on that water. Stay safe this summer and avoid those areas of the beach that seem unusually colorful.

Thought? Comments? I’d love to hear them!

Posted in About James J. Murray, Bacterial Beach Water Contamination, Beach Water Sickness, Biological Poisons, Blog Trends, Blog Writers, Blogging, Cyanobacteria Poisoning, Dangers of Contaminated Beach Water, Deadly Beach Contamination, Deadly Beach Microbes, Deadly Plant Poisons, Deadly Poisons Discussed, Florida Beach Contamination, Infections From Fresh Water, Inhaled Neurotoxins, James J. Murray Blog, Lethal Bacteria, Murder Mayhem and Medicine, Murder with Neurotoxins, Neurological Poisons, Neurotoxin Poisons, Neurotoxins, New Blog, Swimming at the Beach Dangers, Toxic Bloom and Beaches, Toxic Bloom Poisoning, Toxins From Water, Uncategorized, Water Poisons | Tagged , , , , , , , , , , , , , , , , , , , , | 2 Comments

Conspiracy Theory Heart Attacks

Heart AttackIn previous blogs (here and here) I’ve discussed how to construct a murder plot using a drug or medical device that could mimic a heart attack that would be virtually undetectable as a murder—the so-called perfect murder weapon!

But there is yet another equally clever drug (two actually) that can create lethal cardiac events while remaining delightfully elusive to the medical examiner.

Calcium Gluconate is a very useful drug to counteract the effects ofIVBag hyperkalemia (too much potassium in the body) that can produce heart arrhythmias. Calcium gluconate is available as a sterile solution that’s given intravenously. It’s also used to counteract an overdose of Epson Salts (magnesium sulfate).

Too much injected calcium gluconate, however, initiates lethal electrolytic imbalances that disrupt the normal levels of sodium, potassium and chloride in the body’s cells. These electrolyte imbalances interfere with and slow the heart to dangerously low levels, eventually creating a heart attack. It should be noted that a lethal dose of calcium gluconate can only be achieved with the injectable form since an oral dose is absorbed much too slowly.

sweatingThe initial symptoms of a toxic dose of calcium gluconate include skin redness or flushing, a sensation of warmth or heat with a possible rash, sweating, nausea and vomiting, a tingling sensation, and an irregular and slow heartbeat.

The impatient murderer might even add a second injection—potassium phosphate. By doing so, the calcium and phosphate in these solutions will interact and form an insoluble bond that creates what’s known as an aggregate anaphylaxis—severe hypertension and right ventricular heart failure. A hint to the murder mystery writer: When calcium gluconate and potassium phosphate solutions are mixed together, they form an insoluble precipitant. Therefore, they must be injected separately to prevent precipitate formation until they’re in the victim’s bloodstream.

When I was a clinical pharmacist, I formulated and prepared intravenousTPN solutions feeding solutions for patients who could not tolerate oral nutrition. I had to make sure that the calcium gluconate and potassium phosphate solutions remained separated by mixing in the calcium gluconate solution as one of the FIRST ingredients and adding the potassium phosphate solution as one of the LAST ingredients so that each was dilute enough in the total mixture so as not to interact and form an insoluble complex that would harm my patients.

Thoughts? Comments? I’d love to hear them!

Posted in A How To Blog on Murder Plot Ideas, A How To Blog on Murder Weapons, About James J. Murray, About Medications/Pharmacy, About Murder, About Writing, Aggregate Anaphylaxis, Blog Writers, Blogging, Bloodless Death Scene Writing, Calcium Gluconate and Heart Attacks, Calcium Gluconate and Murder, Chemical Poisons, Chemicals Used For Murder, Designer Drug Deaths, Designing Murder Plots, Dramatic Murder Weapons, Drugs Used to Murder, Electrolyte Imbalances and Heart Attacks, How to Choose a Murder Weapon for a Plot Idea, How To Write A BloodLess Murder Scene, Ideas for Murder Scenes, Instruments of Death, James J. Murray Blog, Killing Off Characters in Writing, Lethal Agents and Murder, Lethal Chemicals in Murder Mysteries, Murder Mayhem and Medicine, Murder Weapons Discussed, New Blog, New Methods of Murder, New Methods To Kill Characters in Your Novel, Pharmacy/Pharmaceuticals, Plotting Murder Scenes, Prescription For Murder Blog, The Art of Storytelling, the perfect murder weapon, The Science of Murder, Tools of Murder, Unique Murder Plots, Unique Murder Weapons, Ways to Murder, Writing Death Scenes | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , | 2 Comments

Something New About Nitrosamines!

It’s relatively OLD NEWS regarding the dangers of nitrosamines in the processed foods we eat. Exposing foods, particularly those with higher nitrite Bacon Fryingcontents, to high temperatures (such as in grilling and frying) cause the nitrites and amines in those foods to transform into nitrosamines. Bacon, hot dogs, other cured meats and certain cheeses that are preserved with nitrite pickling salt are prime sources of nitrites in our food supply. However, many vegetables also contain nitrites since nitrate and nitrite chemicals are found in the fertilizers used in farming.

The resulting nitrosamines that can form during high-temperature cooking have been determined to be carcinogenic. Further studies indicate that they may play a role in Alzheimer’s brain degeneration. Other studies have linked nitrosamines to Parkinson’s disease, diabetes, fatty liver disease and even obesity.

Nitrates and nitrites are added to foods as preservatives to prevent salmonella production primarily in meat products. Sodium nitrite is responsible for the pink color in bologna. Leafy greens also have high levels of nitrites that come from the fertilizers and natural nitrites in the soil, but these don’t seem to have the same effect on our bodies as the nitrites that are artificially added to meat products.

There is one exception, however, that I found most interesting and this isSpinach particularly what I wanted to share with you. If you are attempting to limit your nitrite consumption from the foods you consume, this is an important helpful tip. DO NOT REHEAT SPINACH!!

Spinach is abundant in many vitamins, minerals and antioxidants, but it also contains high levels of nitrites (a natural result of the plant absorbing nitrites from the soil as it grows—even in organically grown spinach). Others dispute this claim as pure fantasy and state that the idea of reheating spinach as a dangerous action is merely a myth.

Cooked SpinachI say act cautiously! When possible, eat spinach fresh and uncooked. If you decide to use spinach in a cooked recipe, don’t reheat the spinach dish the next day because the additional heat may transform the nitrites in the spinach to dangerous nitrosamines.

My Motto:

Uncooked Spinach => Healthy Eating!

Reheating Spinach => An Unwise Eating Choice!

Thoughts? Comments? Disputes? I’d love to hear them!

Posted in About James J. Murray, Blog Writers, Blogging, Cooked Spinach is Dangerous, Cooked Spinach Myth, Food Myths, Food Source Poisons, Food Trends, Foods For Health, Foods That Kill, How to Use Commas Properly, James J. Murray Blog, Lethal Botanicals, Murder Mayhem and Medicine, New Blog, Nitrates and Nitrites in Leafy Greens, Nitrosamines and Spinach, Prescription For Murder Blog | Tagged , , , , , , , , , , , , , , , , , , , , , , , | 2 Comments

TOXIDROMES: Wet vs Dry Symptoms

Medical ExaminerIn last week’s blog, I introduced the concept of toxidromes—defined as a group of specific symptoms and clues which medical examiners use to identify the specific substance used to poison a victim.

In that blog, I discussed two of the most popularDilated Pupils toxidrome categories in modern fiction—Opiod/Opiate Toxidromes and Stimulant Drug Toxidromes. I stated that a central clue to identifying one of those lethal substances was to “look at the eyes” because depressant drugs such as opiates constrict the pupils and stimulant drugs dilate the pupils.

Today I’d like to continue the discussion of toxidromes by presenting two other drug categories that also have telltale clues involving the victim’s eyes and which can lead to a misdiagnosis of a lethal substance. A seasoned murder mystery writer always considers other hidden clues to construct a convincing story and to solve the murder in a believable and accurate fashion, and I hope this blog helps further that cause.

In last week’s blog, I mentioned that there were six general categories of toxidromes in modern toxicology: Opiod, Stimulant, Anticholinergic, Cholinergic, Sedative/Hypnotic and Serotonin Syndrome Substances.

Like those of opiod and stimulant drugs, anticholinergic and cholinergic toxidromes also affect the pupils in a specific telltale manner, and that might lead your medical professional character to a wrong conclusion about the lethal substance unless that character looks for further clues. Anticholinergic and cholinergic drugs produce more specific signs of an overdose that distinguish them from other toxic substances.

Without going into the complicated science behind the mechanism of how anticholinergic vs cholinergic drugs work in the body, the following is a brief discussion of the best ways to identify these drugs as lethal substances in a murder mystery.

Anticholinergic drugs involve several classes of drugs that include antihistamines, tricyclic antidepressants, muscle relaxants, Dry As A Boneantipsychotic drugs, anti-nausea patches and even some asthma medications. The common symptoms of an overdose for all of these drugs are stated as, “hot, dry, blind, red and mad!” The ways medical examiners remember toxic symptoms of these drugs are as follows: “hot as a hare, dry as a bone, blind as a bat, red as a beet and mad as a hatter.” Anticholinergic drugs also cause the pupils of the eye to dilate.

Therefore, it’s important to introduce other telltale signs of an overdose besides the size of the victim’s pupils in your writing. A combination of the above symptoms surely should provide interesting drama in a murder scene and give plenty of clues to your police and medical professional characters to identify the lethal substance and tie it back to your villain.

Cholinergic drugs, on the other hand, produce very WET side effects and the acronym SLUDGE is used most often to remember the symptoms of an overdose of these drugs. SLUDGE refers to Salivation, Lacrimation (tearing), Urination, Diarrhea, GI distress and Emesis. Substances in the generalSludge cholinergic category include muscarine-containing mushrooms, several nerve agents, nicotine, and a variety of insecticides. Cholinergic drugs, however, produce constriction of the pupils of the eye and the combination of the above symptoms with pupil dilation help zero in on cholinergic substances as lethal weapons.

The entire subject of toxidromes can be very complicated and confusing. By doing some basic research into a few simple diagnostic clues, however, a writer can make solving the murder in his/her mystery novel very entertaining for the reader and achieve a level of believability that transforms good writing into GREAT WRITING!

Thoughts? Comments? I’d like to hear them!

********************************************

LIKE MURDER MYSTERIES?  

         HOW ABOUT INTERNATIONAL THRILLERS?

 J Published Novels Collage-2

Check out James J. Murray, Author and his books on:

Amazon                    Facebook                 Goodreads

Posted in A How To Blog on Murder Plot Ideas, A How To Blog on Murder Weapons, About James J. Murray, About Murder, About Writing, Achieving Writing Perfection, All About Murder, Anticholinergic Toxidromes, Blog Writers, Blogging, Bloodless Death Scene Writing, Chemical Poisons, Chemical Weapons Discussions, Chemicals Used For Murder, Cholinergic Toxidromes, Deadly Poisons Discussed, Designer Poisons Used For Murder, Designing Murder Plots, Developing Story Plots, Developing Storyline Ideas, Developing Writing Skills, Difficult to Solve Murders, Dramatic Murder Weapons, Drugs Used For Murder, How to Choose a Murder Weapon for a Plot Idea, Ideas for Murder Scenes, Instruments of Death, Interesting Murder Weapons, James J. Murray Blog, Killing Off Characters in Writing, Lethal Anticholinergic Drug Symptoms, Lethal Chemical Poisons, Lethal Chemicals in Murder Mysteries, Lethal Cholinergic Drug Symptoms, Methods of Murder, Murder Mayhem and Medicine, Murder Weapons, Murder Weapons Discussed, Murder With Drugs, New Blog, New Methods of Murder, Pharmacy/Pharmaceuticals, Poisons and Murder, Poisons Used For Murder, Prescription For Murder Blog, The Science of Murder, The Writings of James J. Murray, Tools of Fiction Writing, Tools of Murder, Toxidromes and Murder, Toxidromes and Murder Mysteries, Toxidromes in Murder Mysteries, Toxidromes to Identify a Poison, Toxidromes to Solve Murders, Unique Lethal Compounds, Unique Murder Plots, Unique Murder Weapons, Ways to Murder, Writing Death Scenes, Writing Dramatic Murder Scenes | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment